Im not vaccinated myself but I heard from some people close to me they didn't feel good at all after 2nd dose of phitzer. This pandemic, virus since beginning is shady we don't know where it come from or anything about it. How can some people die, and some others not even have sympthoms. First they were saying there won't be a vaccine for 4 years, now you have 10 different ones to choose from. But the worst thing is none of them seems to guarantee 100% protection. One partner of mine from Italy, told me his collegue 52 years old died from covid19 after 3 weeks being sick, but she was vaccinated with 1 dose only of phitzer. I asked him are they sure she died from covid he said 100%
That's basic biology, it doesn't require shady conspiracies to make sense of it. Everyone is different. Your diet is different, your lifestyle is different, your exposure to chemicals in the environment you live in will be different and your genetics will be different.
The basic template of how the immune system should work is the same, but there are environmental and genetic conditions that make that your innate immune system could be either normal, stronger or weaker than the mean.
And all this nonsense that "it doesn't offer 100% protection", there are never certainties in the world, not even in physics. What we CAN do is to reduce likelihood of something happening, and in medicine is always an equation about risk and benefit.
Even fever is a "natural" immune response that plays with the likelihood of killing an infection with heat before it toasts your your body's cells, most times it works but sometimes it doesn't and you can die from it. The same logic is applied with chemotherapy, the drugs stop cellular reproduction to stop the cancer cells from reproducing, but it also affects every cell in your body as well and it is the hope that it will kill the cancer cells in your body first before the drugs kill you. It is always a calculated risk and playing with probabilities, and there are no certainties.
Historically flu vaccines have about 40% of efficacy. The fact that mRNA vaccines could offer 90%+ in preventing infection it is a historical milestone, it is truly a homerun in molecular biology.
But that's only the cherry on the top, the true purpose of a vaccine is always PREVENTING DEATH. Controlling contagiousness is just an extra. Before vaccines existed, we had variolation and that had a fatality rate of 2%, but nobody even doubted in applying it as it was way better than smallpox's 40% fatality rate.
It is always an equation of risk benefit, and currently the benefits of getting a vaccine are overwhelmingly evident. Every single "side effect" you may get from the vaccine is 10x worse with a "natural infection".
The fact that most vaccines usually take half a decade to develop is due to the traditional way that vaccines are done. Every single vaccine has been following the following process:
1) Isolate the virus
2) Make it replicate in chicken eggs or in monkey kidneys
3) Collect them and inactivate them by weakening it with chemicals
4) Test that it doesn't have pathogens in your vaccine.
And that is only if the process itself has been vetted and the efficacy of the vaccine has been thoroughly tested with animals and humans.
If it is a novel development you have to add previous steps:
0) Clinical trials with humans
-1) Regulatory authorization for tests on humans
-2) Animal trials
-3) In Vivo experiments
-4) In Vitro experiments
The reason that the vaccines for COVID has been so fast, it is obviously because it was given a global priority to it. Bureaucracy has been simplified, clinical trials have been combined to overlap stages. But mainly the development of this new way of producing vaccines doesn't require the "capture" of a live sample of the virus to make them reproduce in bioreactors, which is messy as you can imagine.
That is the revolutionary aspect of the mRNA vaccines.
We advanced a lot with DNA sequencing, and we also had DNA printers for a while.
So if a team in the antipodes of the planet finds a virus, they can sequence the DNA and then simply email it to a lab in Europe and literally start printing it out and bottling it. No more waiting for weeks for eggs or kidneys to reproduce viruses to then harvesting them, weakening them, etc...
One of the main reasons we couldn't eradicate influenza is because it can mutate faster than what we could produce vaccines. But right now the tide has changed, we can now produce vaccines for new mutations in a week instead of months, not only that we can precisely engineer antibodies to produce and not only to viral infections, we could manufacture a protein that actually works like a marker for cancer cells. mRNA vaccines will open a new chapter in immunotherapy.
Btw, you MUST get two doses of the vaccine otherwise you won't be protected enough. Also, it is better if you space the vaccines about four months between them to get the optimal reaction.
Also, you WON'T be protected until 14 days has passed from getting vaccinated, as that is the time that it takes for your body to recognize the "threat" and start activating your immune system.
If you get infected with COVID the next day after getting a vaccination, it will be as if you weren't vaccinated at all.
The activation of T-Cells takes between one or two weeks.
